human PTPN9 shRNA silencing AAV

Name
AAV-h-PTPN9-shRNA

Cat No
shAAV-220330

Availability
4-5 weeks

This is an AAV expressing shRNA for silencing of Human PTPN9.

shAAV-220330

AAV-h-PTPN9-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human PTPN9 (protein tyrosine phosphatase, non-receptor type 9). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

shRNA Knockdown (%)

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

MEG2; PTPMEG2

Description (Vector)

PTPN9 is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP contains an N-terminal domain that shares a significant similarity with yeast SEC14, which is a protein that has phosphatidylinositol transfer activity and is required for protein secretion through the Golgi complex in yeast. This PTP was found to be activated by polyphosphoinositide, and is thought to be involved in signaling events regulating phagocytosis.

Gene ID

5780

Gene Name (Vector)

protein tyrosine phosphatase, non-receptor type 9

Gene Symbol

PTPN9

HGNC ID

HGNC:9661

ORF Size (aa)

1782

ORF Size (bp)

1782 bp

RefSeq ID

NM_002833

RefSeq Synonyms

NM_002833, BC071574, BC010863,

Species

human

UniGene ID

Hs.445775

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.