human PTGR2 shRNA silencing AAV

Name
AAV-h-PTGR2-shRNA

Cat No
shAAV-220255

Availability
4-5 weeks

This is an AAV expressing shRNA for silencing of Human PTGR2.

shAAV-220255

AAV-h-PTGR2-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human PTGR2 (prostaglandin reductase 2). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

shRNA Knockdown (%)

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

HEL-S-298; PGR2; ZADH1

Description (Vector)

PTGR2 encodes an enzyme involved in the metabolism of prostaglandins. The encoded protein catalyzes the NADPH-dependent conversion of 15-keto-prostaglandin E2 to 15-keto-13,14-dihydro-prostaglandin E2. This protein may also be involved in regulating activation of the peroxisome proliferator-activated receptor. Alternative splicing results in multiple transcript variants.

Gene ID

145482

Gene Name (Vector)

prostaglandin reductase 2

Gene Symbol

PTGR2

HGNC ID

HGNC:20149

ORF Size (aa)

1056

ORF Size (bp)

1056 bp

RefSeq ID

NM_152444

RefSeq Synonyms

NM_152444, NM_001146155, NM_001146154, BC059364,

Species

human

UniGene ID

Hs.632344

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.