human PTCHD1 shRNA silencing AAV

Name
AAV-h-PTCHD1-shRNA

Cat No
shAAV-220216

Availability
6-8 weeks

This is an AAV expressing shRNA for silencing of Human PTCHD1.

shAAV-220216

AAV-h-PTCHD1-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human PTCHD1 (patched domain containing 1). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

AUTSX4

Description (Vector)

PTCHD1 encodes a membrane protein with a patched domain. The encoded protein is similar to Drosophila proteins which act as receptors for the morphogen sonic hedgehog. Deletions in this gene, which is located on the X chromosome, are associated with intellectual disability and autism (PMID: 21091464, PMID: 20844286).

Gene ID

139411

Gene Name (Vector)

patched domain containing 1

Gene Symbol

PTCHD1

HGNC ID

HGNC:26392

ORF Size (aa)

2352

ORF Size (bp)

2352 bp

RefSeq ID

NM_173495

RefSeq Synonyms

NM_173495, BC121061,

Species

human

UniGene ID

Hs.319503

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.