human PSMB6 shRNA silencing AAV

Name
AAV-h-PSMB6-shRNA

Cat No
shAAV-220126

Availability
4-5 weeks

This is an AAV expressing shRNA for silencing of Human PSMB6.

shAAV-220126

AAV-h-PSMB6-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human PSMB6 (proteasome subunit beta 6). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

shRNA Knockdown (%)

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

DELTA; LMPY; Y

Description (Vector)

The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. The encoded protein is a member of the proteasome B-type family, also known as the T1B family, and is a 20S core beta subunit in the proteasome. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.

Gene ID

5694

Gene Name (Vector)

proteasome subunit beta 6

Gene Symbol

PSMB6

HGNC ID

HGNC:9543

ORF Size (aa)

720

RefSeq ID

NM_002798

RefSeq Synonyms

NM_002798, NM_001270481, BC000835,

Species

human

UniGene ID

Hs.77060

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.