human PRSS8 shRNA silencing AAV

Name
AAV-h-PRSS8-shRNA

Cat No
shAAV-220035

Availability
6-8 weeks

This is an AAV expressing shRNA for silencing of Human PRSS8.

shAAV-220035

AAV-h-PRSS8-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human PRSS8 (protease, serine 8). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

CAP1; PROSTASIN

Description (Vector)

PRSS8 encodes a trypsinogen, which is a member of the trypsin family of serine proteases. This enzyme is highly expressed in prostate epithelia and is one of several proteolytic enzymes found in seminal fluid. The proprotein is cleaved to produce a light chain and a heavy chain which are associated by a disulfide bond. It is active on peptide linkages involving the carboxyl group of lysine or arginine.

Gene ID

5652

Gene Name (Vector)

protease, serine 8

Gene Symbol

PRSS8

HGNC ID

HGNC:9491

ORF Size (aa)

1032

ORF Size (bp)

1032 bp

RefSeq ID

NM_002773

RefSeq Synonyms

NM_002773, BC001462,

Species

human

UniGene ID

Hs.75799

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.