human PRSS12 shRNA silencing AAV

Name
AAV-h-PRSS12-shRNA

Cat No
shAAV-220016

Availability
4-5 weeks

This is an AAV expressing shRNA for silencing of Human PRSS12.

shAAV-220016

AAV-h-PRSS12-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human PRSS12 (protease, serine 12). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

shRNA Knockdown (%)

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

BSSP-3; BSSP3; MRT1

Description (Vector)

PRSS12 encodes a member of the trypsin family of serine proteases. Studies in mouse suggest that the encoded enzyme may be involved in structural reorganizations associated with learning and memory. The enzyme is also expressed in Leydig cells in the testis, but its function in this tissue is unknown. Defects in this gene are a cause of mental retardation autosomal recessive type 1 (MRT1).

Gene ID

8492

Gene Name (Vector)

protease, serine 12

Gene Symbol

PRSS12

HGNC ID

HGNC:9477

ORF Size (aa)

1518

ORF Size (bp)

1518 bp

RefSeq ID

NM_003619

RefSeq Synonyms

NM_003619, BC007761,

Species

human

UniGene ID

Hs.654823

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.