human PROX1 shRNA silencing AAV

Name 
AAV-h-PROX1-shRNA
Cat No 
shAAV-219943
Availability
4-5 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Human PROX1.

shAAV-219943
AAV-h-PROX1-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human PROX1 (prospero homeobox 1). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
80
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Description (Vector)
PROX1 is a member of the homeobox transcription factor family. Members of this family contain a homeobox domain that consists of a 60-amino acid helix-turn-helix structure that binds DNA and RNA. PROX1 is conserved across vertebrates and may play an essential role during development. Altered levels of this protein have been reported in cancers of different organs, such as colon, brain, blood, breast, pancreas, liver and esophagus. Alternative splicing results in multiple transcript variants.
Gene ID
5629
Gene Name (Vector)
prospero homeobox 1
Gene Symbol
PROX1
HGNC ID
HGNC:9459
ORF Size (aa)
2214
ORF Size (bp)
2214 bp
RefSeq ID
NM_002763
RefSeq Synonyms
NM_002763, NM_001270616, BC024201,
Species
human
UniGene ID
Hs.585369

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.