human PRAM1 shRNA silencing AAV

Name 
AAV-h-PRAM1-shRNA
Cat No 
shAAV-219708
Availability
6-8 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Human PRAM1.

shAAV-219708
AAV-h-PRAM1-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human PRAM1 (PML-RARA regulated adaptor molecule 1). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
PML-RAR; PRAM-1
Description (Vector)
PRAM1 is similar to FYN binding protein (FYB/SLAP-130), an adaptor protein involved in T cell receptor mediated signaling. This gene is expressed and regulated during normal myelopoiesis. The expression of this gene is induced by retinoic acid and is inhibited by the expression of PML-RARalpha, a fusion protein of promyelocytic leukemia (PML) and the retinoic acid receptor-alpha (RARalpha).
Gene ID
84106
Gene Name (Vector)
PML-RARA regulated adaptor molecule 1
Gene Symbol
PRAM1
HGNC ID
HGNC:30091
ORF Size (aa)
2013
ORF Size (bp)
2013 bp
RefSeq ID
NM_032152
RefSeq Synonyms
NM_032152, BC028012,
Species
human
UniGene ID
Hs.465812

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.