human PPP4R4 shRNA silencing AAV

Name
AAV-h-PPP4R4-shRNA

Cat No
shAAV-219686

Availability
6-8 weeks

This is an AAV expressing shRNA for silencing of Human PPP4R4.

shAAV-219686

AAV-h-PPP4R4-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human PPP4R4 (protein phosphatase 4 regulatory subunit 4). Available with optional GFP reporter or cell-specific promoter.

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Vector Designer

Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

CFAP14; KIAA1622; PP4R4

Description (Vector)

PPP4R4 is a HEAT-like repeat-containing protein. The HEAT repeat is a tandemly repeated, 37-47 amino acid long module occurring in a number of cytoplasmic proteins. Arrays of HEAT repeats form a rod-like helical structure and appear to function as protein-protein interaction surfaces. The repeat-containing region of this protein has some similarity to the constant regulatory domain of the protein phosphatase 2A PR65/A subunit. The function of this particular gene product has not been determined. Alternative splicing has been observed for this gene and two transcript variants encoding distinct isoforms have been identified.

Gene ID

57718

Gene Name (Vector)

protein phosphatase 4 regulatory subunit 4

Gene Symbol

PPP4R4

HGNC ID

HGNC:23788

ORF Size (aa)

2622

ORF Size (bp)

2622 bp

RefSeq ID

NM_020958

RefSeq Synonyms

NM_058237, NM_020958, BC068491,

Species

human

UniGene ID

Hs.259599

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.