human PPP1R1B shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Human PPP1R1B.
shAAV-219628
AAV-h-PPP1R1B-shRNA
Ready-to-use AAV expressing shRNA for silencing of Human PPP1R1B (protein phosphatase 1 regulatory inhibitor subunit 1B). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
DARPP-32; DARPP32
Description (Vector)
PPP1R1B encodes a bifunctional signal transduction molecule. Dopaminergic and glutamatergic receptor stimulation regulates its phosphorylation and function as a kinase or phosphatase inhibitor. As a target for dopamine, this gene may serve as a therapeutic target for neurologic and psychiatric disorders. Multiple transcript variants encoding different isoforms have been found for this gene.
Gene ID
84152
Gene Name (Vector)
protein phosphatase 1 regulatory inhibitor subunit 1B
Gene Symbol
PPP1R1B
HGNC ID
HGNC:9287
ORF Size (aa)
507
RefSeq ID
NM_032192
RefSeq Synonyms
NM_181505, NM_032192, NM_001242464, BC001519,
Species
human
UniGene ID
Hs.286192
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.