human PPM1K shRNA silencing AAV

Name 
AAV-h-PPM1K-shRNA
Cat No 
shAAV-219587
Availability
6-8 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Human PPM1K.

shAAV-219587
AAV-h-PPM1K-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human PPM1K (protein phosphatase, Mg2+/Mn2+ dependent 1K). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
BDP; MSUDMV; PP2Ckappa; PP2Cm; PTMP; UG0882E07
Description (Vector)
PPM1K encodes a member of the PPM family of Mn2+/Mg2+-dependent protein phosphatases. The encoded protein, essential for cell survival and development, is targeted to the mitochondria where it plays a key role in regulation of the mitochondrial permeability transition pore.
Gene ID
152926
Gene Name (Vector)
protein phosphatase, Mg2+/Mn2+ dependent 1K
Gene Symbol
PPM1K
HGNC ID
HGNC:25415
ORF Size (aa)
1119
ORF Size (bp)
1119 bp
RefSeq ID
NM_152542
RefSeq Synonyms
NM_152542, BC037552,
Species
human
UniGene ID
Hs.291000

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.