human PPA2 shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Human PPA2.
shAAV-219496
AAV-h-PPA2-shRNA
Ready-to-use AAV expressing shRNA for silencing of Human PPA2 (pyrophosphatase (inorganic) 2). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
HSPC124; inorganic pyrophosphatase 2, mitochondrial; PPase 2; pyrophosphatase SID6-306; pyrophosphate phospho-hydrolase 2; SCFAI; SCFI; SID6-306
Description (eCommerce)
PPA2 is localized to the mitochondrion, is highly similar to members of the inorganic pyrophosphatase (PPase) family, and contains the signature sequence essential for the catalytic activity of PPase. PPases catalyze the hydrolysis of pyrophosphate to inorganic phosphate, which is important for the phosphate metabolism of cells [taken from NCBI Entrez Gene (Gene ID: 27068)].
Description (Vector)
PPA2 is localized to the mitochondrion, is highly similar to members of the inorganic pyrophosphatase (PPase) family, and contains the signature sequence essential for the catalytic activity of PPase. PPases catalyze the hydrolysis of pyrophosphate to inorganic phosphate, which is important for the phosphate metabolism of cells. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.
Gene ID
27068
Gene Name (eCommerce)
pyrophosphatase (inorganic) 2
Gene Name (Vector)
pyrophosphatase (inorganic) 2
Gene Symbol
PPA2
HGNC ID
HGNC:28883
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
918
Protein Name (eCommerce)
Inorganic pyrophosphatase 2, mitochondrial
RefSeq ID
NM_006903
RefSeq Synonyms
NM_176869, NM_176867, NM_176866, NM_006903, BC057219,
Research Areas
Gene Expression,Kinase/Phosphatase,Mitochondrion,Translational Control
Research Areas (Faceted)
cell_biology,signal_transduction,transcription_translation
Species
human
Target Sentence
PPA2 is localized to the mitochondrion, is highly similar to members of the inorganic pyrophosphatase (PPase) family, and contains the signature sequence essential for the catalytic activity of PPase. PPases catalyze the hydrolysis of pyrophosphate to inorganic phosphate, which is important for the phosphate metabolism of cells [taken from NCBI Entrez Gene (Gene ID: 27068)].
UniGene ID
Hs.654957
UniProt ID (eCommerce)
Q9H2U2
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.