human POU1F1 shRNA silencing AAV

Name
AAV-h-POU1F1-shRNA

Cat No
shAAV-219469

Availability
6-8 weeks

This is an AAV expressing shRNA for silencing of Human POU1F1.

shAAV-219469

AAV-h-POU1F1-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human POU1F1 (POU class 1 homeobox 1). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

CPHD1; GHF-1; Pit-1; PIT1; POU1F1a

Description (Vector)

POU1F1 encodes a member of the POU family of transcription factors that regulate mammalian development. The protein regulates expression of several genes involved in pituitary development and hormone expression. Mutations in this genes result in combined pituitary hormone deficiency. Multiple transcript variants encoding different isoforms have been found for this gene.

Gene ID

5449

Gene Name (Vector)

POU class 1 homeobox 1

Gene Symbol

POU1F1

HGNC ID

HGNC:9210

ORF Size (aa)

873

RefSeq ID

NM_000306

RefSeq Synonyms

NM_001122757, NM_000306, BC152851,

Species

human

UniGene ID

Hs.591654

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.