human POR shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Human POR.
shAAV-219453
AAV-h-POR-shRNA
Ready-to-use AAV expressing shRNA for silencing of Human POR (cytochrome p450 oxidoreductase). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
CPR; CYPOR; P450R
Description (Vector)
POR encodes an endoplasmic reticulum membrane oxidoreductase with an FAD-binding domain and a flavodoxin-like domain. The protein binds two cofactors, FAD and FMN, which allow it to donate electrons directly from NADPH to all microsomal P450 enzymes. Mutations in this gene have been associated with various diseases, including apparent combined P450C17 and P450C21 deficiency, amenorrhea and disordered steroidogenesis, congenital adrenal hyperplasia and Antley-Bixler syndrome.
Gene ID
5447
Gene Name (Vector)
cytochrome p450 oxidoreductase
Gene Symbol
POR
HGNC ID
HGNC:9208
ORF Size (aa)
2043
ORF Size (bp)
2043 bp
RefSeq ID
NM_000941
RefSeq Synonyms
NM_000941, BC034277,
Species
human
UniGene ID
Hs.354056
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.