human POMZP3 shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Human POMZP3.
shAAV-219441
AAV-h-POMZP3-shRNA
Ready-to-use AAV expressing shRNA for silencing of Human POMZP3 (POM121 and ZP3 fusion). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
POM-ZP3; POM121
Description (Vector)
POMZP3 appears to have resulted from a fusion of DNA sequences derived from 2 distinct loci, specifically through the duplication of two internal exons from the POM121 gene and four 3' exons from the ZP3 gene. The 5' end of this gene is similar to the 5` coding region of the POM121 gene which encodes an integral nuclear pore membrane protein. However, the protein encoded by this gene lacks the nuclear pore localization motif. The 3' end of this gene is similar to the last 4 exons of the zona pellucida glycoprotein 3 (ZP3) gene and the encoded protein retains one zona pellucida domain. Multiple protein isoforms are encoded by transcript variants of this gene.
Gene ID
22932
Gene Name (Vector)
POM121 and ZP3 fusion
Gene Symbol
POMZP3
HGNC ID
HGNC:9203
ORF Size (aa)
564
RefSeq ID
NM_012230
RefSeq Synonyms
NM_152992, NM_012230, BC153130, BC148538, BC017101,
Species
human
UniGene ID
Hs.488877
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.