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human POLR2L shRNA silencing AAV

Name 
AAV-h-POLR2L-shRNA
Cat No 
shAAV-219410
Availability
4-5 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Human POLR2L.

shAAV-219410
AAV-h-POLR2L-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human POLR2L (RNA polymerase II subunit L). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
90
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
hRPB7.6; RBP10; RPABC5; RPB10; RPB10beta; RPB7.6
Description (Vector)
POLR2L encodes a subunit of RNA polymerase II, the polymerase responsible for synthesizing messenger RNA in eukaryotes. The product of this gene contains four conserved cysteines characteristic of an atypical zinc-binding domain. Like its counterpart in yeast, this subunit may be shared by the other two DNA-directed RNA polymerases.
Gene ID
5441
Gene Name (Vector)
RNA polymerase II subunit L
Gene Symbol
POLR2L
HGNC ID
HGNC:9199
ORF Size (aa)
204
RefSeq ID
NM_021128
RefSeq Synonyms
NM_021128, BC018649, BC005903,
Species
human
UniGene ID
Hs.441072

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About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.