human PODXL shRNA silencing AAV

Name
AAV-h-PODXL-shRNA

Cat No
shAAV-219332

Availability
4-5 weeks

This is an AAV expressing shRNA for silencing of Human PODXL.

shAAV-219332

AAV-h-PODXL-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human PODXL (podocalyxin like). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

shRNA Knockdown (%)

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

Gp200; PC; PCLP; PCLP-1

Description (Vector)

PODXL encodes a member of the sialomucin protein family. The encoded protein was originally identified as an important component of glomerular podocytes. Podocytes are highly differentiated epithelial cells with interdigitating foot processes covering the outer aspect of the glomerular basement membrane. Other biological activities of the encoded protein include: binding in a membrane protein complex with Na+/H+ exchanger regulatory factor to intracellular cytoskeletal elements, playing a role in hematopoetic cell differentiation, and being expressed in vascular endothelium cells and binding to L-selectin.

Gene ID

5420

Gene Name (Vector)

podocalyxin like

Gene Symbol

PODXL

HGNC ID

HGNC:9171

ORF Size (aa)

1683

ORF Size (bp)

1683 bp

RefSeq ID

NM_005397

RefSeq Synonyms

NM_005397, NM_001018111, BC143318, BC112035, BC093730,

Species

human

UniGene ID

Hs.690098

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.