human PLXNC1 shRNA silencing AAV

Name 
AAV-h-PLXNC1-shRNA
Cat No 
shAAV-219257
Availability
4-5 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Human PLXNC1.

shAAV-219257
AAV-h-PLXNC1-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human PLXNC1 (plexin C1). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
60
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
CD232; PLXN-C1; VESPR
Description (Vector)
PLXNC1 encodes a member of the plexin family. Plexins are transmembrane receptors for semaphorins, a large family of proteins that regulate axon guidance, cell motility and migration, and the immune response. The encoded protein and its ligand regulate melanocyte adhesion, and viral semaphorins may modulate the immune response by binding to this receptor. The encoded protein may be a tumor suppressor protein for melanoma. Alternatively spliced transcript variants have been observed for this gene.
Gene ID
10154
Gene Name (Vector)
plexin C1
Gene Symbol
PLXNC1
HGNC ID
HGNC:9106
ORF Size (aa)
4704
ORF Size (bp)
4704 bp
RefSeq ID
NM_005761
RefSeq Synonyms
NM_005761, BC156867, BC148590,
Species
human
UniGene ID
Hs.584845

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.