human PLDN shRNA silencing AAV

Name 
AAV-h-PLDN-shRNA
Cat No 
shAAV-219153
Availability
4-5 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Human BLOC1S6.

shAAV-219153
AAV-h-PLDN-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human BLOC1S6 (biogenesis of lysosomal organelles complex 1 subunit 6). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
70
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
BLOS6; HPS9; PA; PALLID; PLDN
Description (Vector)
BLOC1S6 may play a role in intracellular vesicle trafficking. It interacts with Syntaxin 13 which mediates intracellular membrane fusion. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some of these variants has not been determined.
Gene ID
26258
Gene Name (Vector)
biogenesis of lysosomal organelles complex 1 subunit 6
Gene Symbol
BLOC1S6
HGNC ID
HGNC:8549
ORF Size (aa)
519
ORF Size (bp)
519 bp
RefSeq ID
NM_012388
RefSeq Synonyms
NM_012388, NM_001311256, NM_001311255, BC004819,
Species
human
UniGene ID
Hs.7037

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.