human PLA2G6 shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Human PLA2G6.
shAAV-219080
AAV-h-PLA2G6-shRNA
Ready-to-use AAV expressing shRNA for silencing of Human PLA2G6 (phospholipase A2 group VI). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
CaI-PLA2; GVI; INAD1; iPLA2; IPLA2-VIA; iPLA2beta; NBIA2; NBIA2A; NBIA2B; PARK14; PLA2; PNPLA9
Description (Vector)
PLA2G6 is an A2 phospholipase, a class of enzyme that catalyzes the release of fatty acids from phospholipids. The encoded protein may play a role in phospholipid remodelling, arachidonic acid release, leukotriene and prostaglandin synthesis, fas-mediated apoptosis, and transmembrane ion flux in glucose-stimulated B-cells. Several transcript variants encoding multiple isoforms have been described, but the full-length nature of only three of them have been determined to date.
Gene ID
8398
Gene Name (Vector)
phospholipase A2 group VI
Gene Symbol
PLA2G6
HGNC ID
HGNC:9039
ORF Size (aa)
2421
ORF Size (bp)
2421 bp
RefSeq ID
NM_003560
RefSeq Synonyms
NM_003560, NM_001199562, NM_001004426, BC051904, BC036742,
Species
human
UniGene ID
Hs.170479
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.