human PHACTR3 shRNA silencing AAV

Name
AAV-h-PHACTR3-shRNA

Cat No
shAAV-218778

Availability
6-8 weeks

This is an AAV expressing shRNA for silencing of Human PHACTR3.

shAAV-218778

AAV-h-PHACTR3-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human PHACTR3 (phosphatase and actin regulator 3). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

C20orf101; H17739; PPP1R123; SCAPIN1; SCAPININ

Description (Vector)

PHACTR3 is associated with the nuclear scaffold in proliferating cells. It was found to bind to the catalytic subunit of protein phosphatase-1 (PP1) and inhibit PP1 activity, suggesting that this protein may function as a regulatory subunit of PP1. Alternative splicing at this locus results in several transcript variants encoding different isoforms.

Gene ID

116154

Gene Name (Vector)

phosphatase and actin regulator 3

Gene Symbol

PHACTR3

HGNC ID

HGNC:15833

ORF Size (aa)

1680

ORF Size (bp)

1680 bp

RefSeq ID

NM_080672

RefSeq Synonyms

NM_183246, NM_183244, NM_080672, NM_001281507, NM_001199506, NM_001199505, BC117364, BC117362, BC108303,

Species

human

UniGene ID

Hs.473218

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.