human PGM3 shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Human PGM3.
shAAV-218764
AAV-h-PGM3-shRNA
Ready-to-use AAV expressing shRNA for silencing of Human PGM3 (phosphoglucomutase 3). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
acetylglucosamine phosphomutase; AGM1; IMD23; N-acetylglucosamine-phosphate mutase; N-acetylglucosamine-phosphate mutase 1; PAGM; PGM 3; phosphoacetylglucosamine mutase; Phosphoglucomutase-3
Description (eCommerce)
Phosphoglucomutase-3 (PGM3) is a member of the phosphohexose mutase family. PGM3 mediates both glycogen formation and utilization by catalyzing the interconversion of glucose-1-phosphate and glucose-6-phosphat [taken from NCBI Entrez Gene (Gene ID: 5238)].
Description (Vector)
PGM3 encodes a member of the phosphohexose mutase family. The encoded protein mediates both glycogen formation and utilization by catalyzing the interconversion of glucose-1-phosphate and glucose-6-phosphate. A non-synonymous single nucleotide polymorphism in this gene may play a role in resistance to diabetic nephropathy and neuropathy. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
Gene ID
5238
Gene Name (eCommerce)
phosphoglucomutase 3
Gene Name (Vector)
phosphoglucomutase 3
Gene Symbol
PGM3
HGNC ID
HGNC:8907
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
1629
ORF Size (bp)
1629 bp
Protein Name (eCommerce)
Phosphoacetylglucosamine mutase
RefSeq ID
NM_015599
RefSeq Synonyms
NM_015599, NM_001199919, NM_001199918, NM_001199917, BC001258,
Research Areas
Metabolism/Metabolic Process,Translational Control
Research Areas (Faceted)
cell_biology,metabolism,transcription_translation
Species
human
Target Sentence
Phosphoglucomutase-3 (PGM3) is a member of the phosphohexose mutase family. PGM3 mediates both glycogen formation and utilization by catalyzing the interconversion of glucose-1-phosphate and glucose-6-phosphat [taken from NCBI Entrez Gene (Gene ID: 5238)].
UniGene ID
Hs.708038
UniProt ID (eCommerce)
O95394
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.