human PF4 shRNA silencing AAV

Name 
AAV-h-PF4-shRNA
Cat No 
shAAV-218651
Availability
6-8 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Human PF4.

shAAV-218651
AAV-h-PF4-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human PF4 (platelet factor 4). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
CXCL4; PF-4; SCYB4
Description (Vector)
PF4 encodes a member of the CXC chemokine family. This chemokine is released from the alpha granules of activated platelets in the form of a homotetramer which has high affinity for heparin and is involved in platelet aggregation. This protein is chemotactic for numerous other cell type and also functions as an inhibitor of hematopoiesis, angiogenesis and T-cell function.
Gene ID
5196
Gene Name (Vector)
platelet factor 4
Gene Symbol
PF4
HGNC ID
HGNC:8861
ORF Size (aa)
306
RefSeq ID
NM_002619
RefSeq Synonyms
NM_002619, BC112093, BC093965,
Species
human
UniGene ID
Hs.81564

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.