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human PDSS2 shRNA silencing AAV

Name 
AAV-h-PDSS2-shRNA
Cat No 
shAAV-218558
Availability
4-5 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Human PDSS2.

shAAV-218558
AAV-h-PDSS2-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human PDSS2 (decaprenyl diphosphate synthase subunit 2). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
90
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
bA59I9.3; C6orf210; COQ10D3; DLP1; hDLP1
Description (Vector)
PDSS2 is an enzyme that synthesizes the prenyl side-chain of coenzyme Q, or ubiquinone, one of the key elements in the respiratory chain. The gene product catalyzes the formation of all trans-polyprenyl pyrophosphates from isopentyl diphosphate in the assembly of polyisoprenoid side chains, the first step in coenzyme Q biosynthesis. Defects in this gene are a cause of coenzyme Q10 deficiency.
Gene ID
57107
Gene Name (Vector)
decaprenyl diphosphate synthase subunit 2
Gene Symbol
PDSS2
HGNC ID
HGNC:23041
ORF Size (aa)
1200
ORF Size (bp)
1200 bp
RefSeq ID
NM_020381
RefSeq Synonyms
NM_020381, BC039906,
Species
human
UniGene ID
Hs.718509

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.