human PDE3B shRNA silencing AAV

Name 
AAV-h-PDE3B-shRNA
Cat No 
shAAV-218468
Availability
4-5 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Human PDE3B.

shAAV-218468
AAV-h-PDE3B-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human PDE3B (phosphodiesterase 3B). Available with optional GFP reporter or cell-specific promoter.

Request a Quote

Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
70
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
CGIP1; CGI-PDE B; cGIPDE1; cGMP-inhibited 3',5'-cyclic phosphodiesterase B; cyclic GMP-inhibited phosphodiesterase B; cyclic nucleotide phosphodiesterase; HcGIP1; phosphodiesterase 3B, cGMP-inhibited
Description (eCommerce)
PDE3B (phosphodiesterase 3B) is a cyclic nucleotide phosphodiesterase with a dual-specificity for the second messengers cAMP and cGMP. PDE3B may play a role in fat metabolism.
Gene ID
5140
Gene Name (eCommerce)
phosphodiesterase 3B
Gene Name (Vector)
phosphodiesterase 3B
Gene Symbol
PDE3B
HGNC ID
HGNC:8779
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
3339
ORF Size (bp)
3339 bp
Protein Name (eCommerce)
cGMP-inhibited 3',5'-cyclic phosphodiesterase B
RefSeq ID
NM_000922
RefSeq Synonyms
NM_000922, BC150322, BC150307, BC146828, BC144248, BC136566, BC136565,
Research Areas
Angiogenesis,Cardiology,Cardiovascular,Golgi Apparatus,GPCR Signaling,IGF-1 Signaling,Insulin Signaling,Leptin Signaling,Metabolism/Metabolic Process,Neurobiology,Signal Transduction
Research Areas (Faceted)
cancer,cardiovascular,cell_biology,developmental_biology,metabolism,neurobiology,signal_transduction
Species
human
Target Sentence
PDE3B (phosphodiesterase 3B) is a cyclic nucleotide phosphodiesterase with a dual-specificity for the second messengers cAMP and cGMP. PDE3B may play a role in fat metabolism.
UniGene ID
Hs.445711
UniProt ID (eCommerce)
Q13370

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.