human PCK1 shRNA silencing AAV
Category: AAV > shRNA-Silencing
Cat. No: shAAV-218382
Availability:
6-8 weeks
Name:
AAV-h-PCK1-shRNA
This is an AAV expressing shRNA for silencing of Human PCK1.
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Product Info
- Knockdown
- shRNA screening service available, please inquire about this service or other options.
Viral Details
- Viral Backbone
- Recombinant AAV
- AAV-ITR
- AAV2
- AAV Serotype
- Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
- Promoter
- U6
- Reporter
- eGFP (default), optional CFP, YFP, RFP, mCherry
- Storage Buffer
- PBS/5% Glycerol
Gene Details
- Species
- Human
- Gene Symbol
- PCK1
- Gene Name
- phosphoenolpyruvate carboxykinase 1
- Gene ID
- 5105
- Gene Synonyms
- PEPCK-C; PEPCK1; PEPCKC
- ORF Size
- 1869 bp
- RefSeq#
- NM_002591
- Gene Description
- PCK1 is a main control point for the regulation of gluconeogenesis. The cytosolic enzyme encoded by this gene, along with GTP, catalyzes the formation of phosphoenolpyruvate from oxaloacetate, with the release of carbon dioxide and GDP. The expression of this gene can be regulated by insulin, glucocorticoids, glucagon, cAMP, and diet. Defects in this gene are a cause of cytosolic phosphoenolpyruvate carboxykinase deficiency. A mitochondrial isozyme of the encoded protein also has been characterized.
- UniGene ID
- Hs.1872
- HGNC ID
- HGNC:8724
Related Products
Control Products
Product | Cat No. |
---|---|
AAV1-GFP-U6-shRNA | 7040 |
AAV2-GFP-U6-shRNA | 7041 |
AAV5-GFP-U6-shRNA | 7042 |
AAV6-GFP-U6-shRNA | 7043 |
AAV9-GFP-U6-shRNA | 7045 |
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