human PASK shRNA silencing AAV

Name 
AAV-h-PASK-shRNA
Cat No 
shAAV-218256
Availability
4-5 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Human PASK.

shAAV-218256
AAV-h-PASK-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human PASK (PAS domain containing serine/threonine kinase). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
80
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
hPASK; PAS domain-containing serine/threonine-protein kinase; PASKIN; PAS-kinase; per-arnt-sim (PAS) domain kinase; STK37
Description (eCommerce)
Per-Arnt-Sim (PAS) domain-containing protein kinase (PASK) is an evolutionarily conserved protein present in yeast, flies, and mammals. In, mammals, PASKIN is proposed to play a role in glycogen synthesis and protein translation.
Description (Vector)
PASK encodes a member of the serine/threonine kinase family that contains two PAS domains. Expression of this gene is regulated by glucose, and the encoded protein plays a role in the regulation of insulin gene expression. Downregulation of this gene may play a role in type 2 diabetes. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
Gene ID
23178
Gene Name (eCommerce)
PAS domain containing serine/threonine kinase
Gene Name (Vector)
PAS domain containing serine/threonine kinase
Gene Symbol
PASK
HGNC ID
HGNC:17270
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
3432
ORF Size (bp)
3432 bp
Protein Name (eCommerce)
PAS domain-containing serine/threonine-protein kinase
RefSeq ID
NM_015148
RefSeq Synonyms
NM_015148, NM_001252124, NM_001252122, NM_001252120, NM_001252119, BC063585, BC050565,
Research Areas
Golgi Apparatus,Kinase/Phosphatase,Signal Transduction,Transcription Factor/Regulator,Translational Control
Research Areas (Faceted)
cell_biology,signal_transduction,transcription_translation
Species
human
Target Sentence
Per-Arnt-Sim (PAS) domain-containing protein kinase (PASK) is an evolutionarily conserved protein present in yeast, flies, and mammals. In, mammals, PASKIN is proposed to play a role in glycogen synthesis and protein translation.
UniGene ID
Hs.397891
UniProt ID (eCommerce)
Q96RG2

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.