human OTOS shRNA silencing AAV

Name 
AAV-h-OTOS-shRNA
Cat No 
shAAV-217993
Availability
6-8 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Human OTOS.

shAAV-217993
AAV-h-OTOS-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human OTOS (otospiralin). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
OTOSP
Description (Vector)
Otospiralin is synthesized by nonsensory cells (fibrocytes) of the inner ear, and downregulation of otospiralin in guinea pigs leads to deafness (Lavigne-Rebillard et al., 2003 (PubMed 12687421)).(supplied by OMIM, Mar 2008)
Gene ID
150677
Gene Name (Vector)
otospiralin
Gene Symbol
OTOS
HGNC ID
HGNC:22644
ORF Size (aa)
270
RefSeq ID
NM_148961
RefSeq Synonyms
NM_148961, BC105087, BC105085,
Species
human
UniGene ID
Hs.148586

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.