human OPLAH shRNA silencing AAV

Name 
AAV-h-OPLAH-shRNA
Cat No 
shAAV-217431
Availability
6-8 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Human OPLAH.

shAAV-217431
AAV-h-OPLAH-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human OPLAH (5-oxoprolinase (ATP-hydrolysing)). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
5-Opase; OPLA; OPLAHD
Description (Vector)
OPLAH acts as a homodimer, using ATP hydrolysis to catalyze the conversion of 5-oxo-L-proline to L-glutamate. Defects in this gene are a cause of 5-oxoprolinase deficiency (OPLAHD).
Gene ID
26873
Gene Name (Vector)
5-oxoprolinase (ATP-hydrolysing)
Gene Symbol
OPLAH
HGNC ID
HGNC:8149
ORF Size (aa)
3864
ORF Size (bp)
3864 bp
RefSeq ID
NM_017570
RefSeq Synonyms
NM_017570, BC150206, BC142672, BC140370,
Species
human
UniGene ID
Hs.305882

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.