human OCA2 shRNA silencing AAV

Name
AAV-h-OCA2-shRNA

Cat No
shAAV-217328

Availability
6-8 weeks

This is an AAV expressing shRNA for silencing of Human OCA2.

shAAV-217328

AAV-h-OCA2-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human OCA2 (OCA2 melanosomal transmembrane protein). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

BEY; BEY1; BEY2; BOCA; D15S12; EYCL; EYCL2; EYCL3; HCL3; P; PED; SHEP1

Description (Vector)

OCA2 encodes the human homologue of the mouse p (pink-eyed dilution) gene. The encoded protein is believed to be an integral membrane protein involved in small molecule transport, specifically tyrosine - a precursor of melanin. Mutations in this gene result in type 2 oculocutaneous albinism.

Gene ID

4948

Gene Name (Vector)

OCA2 melanosomal transmembrane protein

Gene Symbol

OCA2

HGNC ID

HGNC:8101

ORF Size (aa)

2445

ORF Size (bp)

2445 bp

RefSeq ID

NM_000275

RefSeq Synonyms

NM_001300984, NM_000275, BC012097,

Species

human

UniGene ID

Hs.654411

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.