human NUP88 shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Human NUP88.
shAAV-217262
AAV-h-NUP88-shRNA
Ready-to-use AAV expressing shRNA for silencing of Human NUP88 (nucleoporin 88). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Description (Vector)
The nuclear pore complex is a massive structure that extends across the nuclear envelope, forming a gateway that regulates the flow of macromolecules between the nucleus and the cytoplasm. Nucleoporins, a family of 50 to 100 proteins, are the main components of the nuclear pore complex in eukaryotic cells. The protein encoded by this gene belongs to the nucleoporin family and is associated with the oncogenic nucleoporin CAN/Nup214 in a dynamic subcomplex. This protein is also overexpressed in a large number of malignant neoplasms and precancerous dysplasias.
Gene ID
4927
Gene Name (Vector)
nucleoporin 88
Gene Symbol
NUP88
HGNC ID
HGNC:8067
ORF Size (aa)
2226
ORF Size (bp)
2226 bp
RefSeq ID
NM_002532
RefSeq Synonyms
NM_002532, NM_001320653, BC000335,
Species
human
UniGene ID
Hs.584784
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.