human NUP155 shRNA silencing AAV

Name
AAV-h-NUP155-shRNA

Cat No
shAAV-217235

Availability
4-5 weeks

This is an AAV expressing shRNA for silencing of Human NUP155.

shAAV-217235

AAV-h-NUP155-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human NUP155 (nucleoporin 155). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

shRNA Knockdown (%)

70

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

155 kDa nucleoporin; ATFB15; N155; nuclear pore complex protein Nup155; nucleoporin 155kD; nucleoporin 155kDa; Nucleoporin Nup155

Description (eCommerce)

Nucleoporin 155 kDa (NUP155) is an essential component of nuclear pore complex. Nucleoporins may be involved both in binding and translocating proteins during nucleocytoplasmic transport [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/O75694].

Description (Vector)

Nucleoporins are the main components of the nuclear pore complex (NPC) of eukaryotic cells. They are involved in the bidirectional trafficking of molecules, especially mRNAs and proteins, between the nucleus and the cytoplasm. The protein encoded by this gene does not contain the typical FG repeat sequences found in most vertebrate nucleoporins. Two protein isoforms are encoded by transcript variants of this gene.

Gene ID

9631

Gene Name (eCommerce)

nucleoporin 155

Gene Name (Vector)

nucleoporin 155

Gene Symbol

NUP155

HGNC ID

HGNC:8063

NCBI Taxonomy ID (eCommerce)

9606.0

ORF Size (aa)

4176

ORF Size (bp)

4176 bp

Protein Name (eCommerce)

Nuclear pore complex protein Nup155

RefSeq ID

NM_004298

RefSeq Synonyms

NM_153485, NM_004298, NM_001278312, BC039257,

Research Areas

Cell Cycle,Gene Expression,Host-Virus Interactions,Immunology,Metabolism/Metabolic Process,mRNA Processing,mRNA Transport,Ribonucleoprotein Transport,RNA Processing,RNA Transport,Transport

Research Areas (Faceted)

cell_biology,cell_cycle,genetics,transcription_translation,infectious_disease,immunology,metabolism

Species

human

Target Sentence

Nucleoporin 155 kDa (NUP155) is an essential component of nuclear pore complex. Nucleoporins may be involved both in binding and translocating proteins during nucleocytoplasmic transport [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/O75694].

UniGene ID

Hs.547696

UniProt ID (eCommerce)

O75694

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.