human NUDT6 shRNA silencing AAV

Name 
AAV-h-NUDT6-shRNA
Cat No 
shAAV-217220
Availability
4-5 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Human NUDT6.

shAAV-217220
AAV-h-NUDT6-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human NUDT6 (nudix hydrolase 6). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
90
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
ASFGF2; FGF-AS; FGF2AS; GFG-1; GFG1
Description (Vector)
NUDT6 overlaps and lies on the opposite strand from FGF2 gene, and is thought to be the FGF2 antisense gene. The two genes are independently transcribed, and their expression shows an inverse relationship, suggesting that this antisense transcript may regulate FGF2 expression. NUDT6 has also been shown to have hormone-regulatory and antiproliferative actions in the pituitary that are independent of FGF2 expression. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Gene ID
11162
Gene Name (Vector)
nudix hydrolase 6
Gene Symbol
NUDT6
HGNC ID
HGNC:8053
ORF Size (aa)
951
ORF Size (bp)
951 bp
RefSeq ID
NM_007083
RefSeq Synonyms
NM_198041, NM_007083, BC009842,
Species
human
UniGene ID
Hs.558459

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.