human NTSR2 shRNA silencing AAV

Name
AAV-h-NTSR2-shRNA

Cat No
shAAV-217171

Availability
6-8 weeks

This is an AAV expressing shRNA for silencing of Human NTSR2.

shAAV-217171

AAV-h-NTSR2-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human NTSR2 (neurotensin receptor 2). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

NTR2

Description (Vector)

NTSR2 belongs to the G protein-coupled receptor family that activate a phosphatidylinositol-calcium second messenger system. Binding and pharmacological studies demonstrate that this receptor binds neurotensin as well as several other ligands already described for neurotensin NT1 receptor. However, unlike NT1 receptor, this gene recognizes, with high affinity, levocabastine, a histamine H1 receptor antagonist previously shown to compete with neurotensin for low-affinity binding sites in brain. These activities suggest that this receptor may be of physiological importance and that a natural agonist for the receptor may exist.

Gene ID

23620

Gene Name (Vector)

neurotensin receptor 2

Gene Symbol

NTSR2

HGNC ID

HGNC:8040

ORF Size (aa)

1155

ORF Size (bp)

1155 bp

RefSeq ID

NM_012344

RefSeq Synonyms

NM_012344, BC037776, BC022501,

Species

human

UniGene ID

Hs.131138

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.