human PLK4 shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Human PLK4.
shAAV-219215
AAV-h-PLK4-shRNA
Ready-to-use AAV expressing shRNA for silencing of Human PLK4 (polo like kinase 4). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
MCCRP2; SAK; STK18
Description (Vector)
PLK4 encodes a member of the polo family of serine/threonine protein kinases. The protein localizes to centrioles, complex microtubule-based structures found in centrosomes, and regulates centriole duplication during the cell cycle. Three alternatively spliced transcript variants that encode different protein isoforms have been found for this gene.
Gene ID
10733
Gene Name (Vector)
polo like kinase 4
Gene Symbol
PLK4
HGNC ID
HGNC:11397
ORF Size (aa)
2913
ORF Size (bp)
2913 bp
RefSeq ID
NM_014264
RefSeq Synonyms
NM_014264, NM_001190801, NM_001190799, BC036023,
Species
human
UniGene ID
Hs.172052
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.