human NRXN1 shRNA silencing AAV

Name 
AAV-h-NRXN1-shRNA
Cat No 
shAAV-217105
Availability
6-8 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Human NRXN1.

shAAV-217105
AAV-h-NRXN1-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human NRXN1 (neurexin 1). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
Hs.22998; PTHSL2; SCZD17
Description (Vector)
Neurexins function in the vertebrate nervous system as cell adhesion molecules and receptors. Two neurexin genes are among the largest known in human (NRXN1 and NRXN3). By using alternate promoters, splice sites and exons, predictions of hundreds or even thousands of distinct mRNAs have been made. Most transcripts use the upstream promoter and encode alpha-neurexin isoforms; fewer transcripts are produced from the downstream promoter and encode beta-neurexin isoforms. Alpha-neurexins contain epidermal growth factor-like (EGF-like) sequences and laminin G domains, and they interact with neurexophilins. Beta-neurexins lack EGF-like sequences and contain fewer laminin G domains than alpha-neurexins. The RefSeq Project has decided to create only a few representative transcript variants of the multitude that are possible.
Gene ID
9378
Gene Name (Vector)
neurexin 1
Gene Symbol
NRXN1
HGNC ID
HGNC:8008
ORF Size (aa)
4491
ORF Size (bp)
4491 bp
RefSeq ID
NM_138735
RefSeq Synonyms
NM_138735, NM_004801, NM_001330097, NM_001330096, NM_001330095, NM_001330094, NM_001330093, NM_001330092, NM_001330091, NM_001330090, NM_001330089, NM_001330088, NM_001330087, NM_001330086, NM_001330085, NM_001330084, NM_001330083, NM_001330082, NM_001330081, NM_001330079, NM_001330078, NM_001330077, NM_001320157, NM_001320156, NM_001135659, BC150247,
Species
human
UniGene ID
Hs.637685

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.