human NR2C2 shRNA silencing AAV

Name 
AAV-h-NR2C2-shRNA
Cat No 
shAAV-217045
Availability
4-5 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Human NR2C2.

shAAV-217045
AAV-h-NR2C2-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human NR2C2 (nuclear receptor subfamily 2 group C member 2). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
80
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
TAK1; TR4
Description (Vector)
Members of the nuclear hormone receptor family, such as NR2C2, act as ligand-activated transcription factors. The proteins have an N-terminal transactivation domain, a central DNA-binding domain with 2 zinc fingers, and a ligand-binding domain at the C terminus. The activated receptor/ligand complex is translocated to the nucleus where it binds to hormone response elements of target genes (Yoshikawa et al., 1996 (PubMed 8661150)).(supplied by OMIM, Mar 2008)
Gene ID
7182
Gene Name (Vector)
nuclear receptor subfamily 2 group C member 2
Gene Symbol
NR2C2
HGNC ID
HGNC:7972
ORF Size (aa)
1593
ORF Size (bp)
1593 bp
RefSeq ID
NM_003298
RefSeq Synonyms
NM_003298, NM_001291694, BC051670,
Species
human
UniGene ID
Hs.555973

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.