human NPC2 shRNA silencing AAV
Category: AAV > shRNA-Silencing
Cat. No: shAAV-216950
Availability:
4-5 weeks
Name:
AAV-h-NPC2-shRNA
This is an AAV expressing shRNA for silencing of Human NPC2.
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Product Info
- Knockdown
- >90% knockdown of mRNA in cultured cells
Viral Details
- Viral Backbone
- Recombinant AAV
- AAV-ITR
- AAV2
- AAV Serotype
- Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
- Promoter
- U6
- Reporter
- eGFP (default), optional CFP, YFP, RFP, mCherry
- Storage Buffer
- PBS/5% Glycerol
Gene Details
- Species
- Human
- Gene Symbol
- NPC2
- Gene Name
- NPC intracellular cholesterol transporter 2
- Gene ID
- 10577
- Gene Synonyms
- EDDM1; HE1
- ORF Size
- 456 bp
- RefSeq#
- NM_006432
- Gene Description
- NPC2 encodes a protein containing a lipid recognition domain. The encoded protein may function in regulating the transport of cholesterol through the late endosomal/lysosomal system. Mutations in this gene have been associated with Niemann-Pick disease, type C2 and frontal lobe atrophy.
- UniGene ID
- Hs.433222
- HGNC ID
- HGNC:14537
Related Products
Control Products
Product | Cat No. |
---|---|
AAV1-GFP-U6-shRNA | 7040 |
AAV2-GFP-U6-shRNA | 7041 |
AAV5-GFP-U6-shRNA | 7042 |
AAV6-GFP-U6-shRNA | 7043 |
AAV9-GFP-U6-shRNA | 7045 |
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