human NLRC5 shRNA silencing AAV

Name 
AAV-h-NLRC5-shRNA
Cat No 
shAAV-216789
Availability
6-8 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Human NLRC5.

shAAV-216789
AAV-h-NLRC5-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human NLRC5 (NLR family CARD domain containing 5). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
CLR16.1; NOD27; NOD4
Description (Vector)
NLRC5 encodes a member of the caspase recruitment domain-containing NLR family. NLRC5 plays a role in cytokine response and antiviral immunity through its inhibition of NF-kappa-B activation and negative regulation of type I interferon signaling pathways.
Gene ID
84166
Gene Name (Vector)
NLR family CARD domain containing 5
Gene Symbol
NLRC5
HGNC ID
HGNC:29933
ORF Size (aa)
5601
ORF Size (bp)
5601 bp
RefSeq ID
NM_032206
RefSeq Synonyms
NM_032206, NM_001330552, BC172510, BC156512,
Species
human
UniGene ID
Hs.528836

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.