human NLGN3 shRNA silencing AAV

Name
AAV-h-NLGN3-shRNA

Cat No
shAAV-216780

Availability
6-8 weeks

This is an AAV expressing shRNA for silencing of Human NLGN3.

shAAV-216780

AAV-h-NLGN3-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human NLGN3 (neuroligin 3). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

HNL3

Description (Vector)

NLGN3 encodes a member of a family of neuronal cell surface proteins. Members of this family may act as splice site-specific ligands for beta-neurexins and may be involved in the formation and remodeling of central nervous system synapses. Mutations in this gene may be associated with autism and Asperger syndrome. Multiple transcript variants encoding distinct isoforms have been identified for this gene.

Gene ID

54413

Gene Name (Vector)

neuroligin 3

Gene Symbol

NLGN3

HGNC ID

HGNC:14289

ORF Size (aa)

2487

ORF Size (bp)

2487 bp

RefSeq ID

NM_018977

RefSeq Synonyms

NM_181303, NM_018977, NM_001321276, NM_001166660, BC051715,

Species

human

UniGene ID

Hs.438877

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.