human NFKBIE shRNA silencing AAV

Name 
AAV-h-NFKBIE-shRNA
Cat No 
shAAV-216652
Availability
4-5 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Human NFKBIE.

shAAV-216652
AAV-h-NFKBIE-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human NFKBIE (NFKB inhibitor epsilon). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
80
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
IKBE
Description (Vector)
NFKBIE binds to components of NF-kappa-B, trapping the complex in the cytoplasm and preventing it from activating genes in the nucleus. Phosphorylation of the encoded protein targets it for destruction by the ubiquitin pathway, which activates NF-kappa-B by making it available to translocate to the nucleus.
Gene ID
4794
Gene Name (Vector)
NFKB inhibitor epsilon
Gene Symbol
NFKBIE
HGNC ID
HGNC:7799
ORF Size (aa)
1503
ORF Size (bp)
1503 bp
RefSeq ID
NM_004556
RefSeq Synonyms
NM_004556, BC166665,
Species
human
UniGene ID
Hs.458276

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.