human NEUROG3 shRNA silencing AAV

Name 
AAV-h-NEUROG3-shRNA
Cat No 
shAAV-216617
Availability
6-8 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Human NEUROG3.

shAAV-216617
AAV-h-NEUROG3-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human NEUROG3 (neurogenin 3). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
Atoh5; bHLHa7; Math4B; NGN-3; ngn3
Description (Vector)
NEUROG3 is a basic helix-loop-helix (bHLH) transcription factor involved in neurogenesis. The encoded protein likely acts as a heterodimer with another bHLH protein. Defects in this gene are a cause of congenital malabsorptive diarrhea 4 (DIAR4).
Gene ID
50674
Gene Name (Vector)
neurogenin 3
Gene Symbol
NEUROG3
HGNC ID
HGNC:13806
ORF Size (aa)
645
RefSeq ID
NM_020999
RefSeq Synonyms
NM_020999, BC126468, BC117488, BC074939, BC074938, BC069098,
Species
human
UniGene ID
Hs.532682

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.