human NEU3 shRNA silencing AAV

Name 
AAV-h-NEU3-shRNA
Cat No 
shAAV-216601
Availability
4-5 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Human NEU3.

shAAV-216601
AAV-h-NEU3-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human NEU3 (neuraminidase 3). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
70
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
SIAL3
Description (Vector)
NEU3 product belongs to a family of glycohydrolytic enzymes which remove sialic acid residues from glycoproteins and glycolipids. It is localized in the plasma membrane, and its activity is specific for gangliosides. It may play a role in modulating the ganglioside content of the lipid bilayer.
Gene ID
10825
Gene Name (Vector)
neuraminidase 3
Gene Symbol
NEU3
HGNC ID
HGNC:7760
ORF Size (aa)
1386
ORF Size (bp)
1386 bp
RefSeq ID
NM_006656
RefSeq Synonyms
NM_006656, BC144059, BC136397,
Species
human
UniGene ID
Hs.191074

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.