human NEK2 shRNA silencing AAV

Name
AAV-h-NEK2-shRNA

Cat No
shAAV-216570

Availability
4-5 weeks

This is an AAV expressing shRNA for silencing of Human NEK2.

shAAV-216570

AAV-h-NEK2-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human NEK2 (NIMA related kinase 2). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

shRNA Knockdown (%)

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

HsPK21; NEK2A; NLK1; PPP1R111; RP67

Description (Vector)

NEK2 encodes a serine/threonine-protein kinase that is involved in mitotic regulation. This protein is localized to the centrosome, and undetectable during G1 phase, but accumulates progressively throughout the S phase, reaching maximal levels in late G2 phase. Alternatively spliced transcript variants encoding different isoforms with distinct C-termini have been noted for this gene.

Gene ID

4751

Gene Name (Vector)

NIMA related kinase 2

Gene Symbol

NEK2

HGNC ID

HGNC:7745

ORF Size (aa)

1338

ORF Size (bp)

1338 bp

RefSeq ID

NM_002497

RefSeq Synonyms

NM_002497, NM_001204183, NM_001204182, BC065932, BC043502,

Species

human

UniGene ID

Hs.153704

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.