human NDUFS2 shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Human NDUFS2.
shAAV-216522
AAV-h-NDUFS2-shRNA
Ready-to-use AAV expressing shRNA for silencing of Human NDUFS2 (NADH:ubiquinone oxidoreductase core subunit S2). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
CI-49
Description (Vector)
NDUFS2 is a core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (complex I). Mammalian mitochondrial complex I is composed of at least 43 different subunits, 7 of which are encoded by the mitochondrial genome, and the rest are the products of nuclear genes. The iron-sulfur protein fraction of complex I is made up of 7 subunits, including this gene product. Complex I catalyzes the NADH oxidation with concomitant ubiquinone reduction and proton ejection out of the mitochondria. Mutations in this gene are associated with mitochondrial complex I deficiency. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Gene ID
4720
Gene Name (Vector)
NADH:ubiquinone oxidoreductase core subunit S2
Gene Symbol
NDUFS2
HGNC ID
HGNC:7708
ORF Size (aa)
1392
ORF Size (bp)
1392 bp
RefSeq ID
NM_004550
RefSeq Synonyms
NM_004550, NM_001166159, BC008868, BC001456, BC000170,
Species
human
UniGene ID
Hs.173611
Recently Viewed Products
Ad-CMV-iCre
Cat No: 1045
Ad-CMV-Caspase 9 (DN)
Cat No: 1044
Ad-CMV-Rb
Cat No: 1043
Ad-CMV-p27
Cat No: 1042
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.