human NACC2 shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Human NACC2.
shAAV-216281
AAV-h-NACC2-shRNA
Ready-to-use AAV expressing shRNA for silencing of Human NACC2 (NACC family member 2). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
BEN domain containing 9; BEND9; BTB (POZ) domain containing 14A; BTB/POZ domain-containing protein 14A; BTBD14; BTBD14A; BTBD31; NAC-2; NACC family member 2, BEN and BTB (POZ) domain containing; nucleus accumbens-associated protein 2; RBB; repressor with BTB domain and BEN domain; transcription repressor with a BTB domain and a BEN domain
Description (eCommerce)
NACC2/BTBD14A functions as a transcriptional repressor through its association with the NuRD complex. NACC2/BTBD14A recruits the NuRD complex to the promoter of MDM2, leading to the repression of MDM2 transcription and subsequent stability of p53/TP53Â [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/Q96BF6].
Gene ID
138151
Gene Name (eCommerce)
NACC family member 2
Gene Name (Vector)
NACC family member 2
Gene Symbol
NACC2
HGNC ID
HGNC:23846
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
1764
ORF Size (bp)
1764 bp
Protein Name (eCommerce)
Nucleus accumbens-associated protein 2
RefSeq ID
NM_144653
RefSeq Synonyms
NM_144653, BC015649,
Research Areas
Cell Biology,Transcription Factor/Regulator
Research Areas (Faceted)
cell_biology,transcription_translation
Species
human
Target Sentence
NACC2/BTBD14A functions as a transcriptional repressor through its association with the NuRD complex. NACC2/BTBD14A recruits the NuRD complex to the promoter of MDM2, leading to the repression of MDM2 transcription and subsequent stability of p53/TP53Â [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/Q96BF6].
UniGene ID
Hs.112895
UniProt ID (eCommerce)
Q96BF6
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.