human NAALAD2 shRNA silencing AAV

Cat. No: shAAV-216271

Availability: 6-8 weeks

Name: AAV-h-NAALAD2-shRNA

This is an AAV expressing shRNA for silencing of Human NAALAD2.

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Knockdown: shRNA screening service available, please inquire about this service or other options.

Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Human
Gene Symbol: NAALAD2
Gene Name: N-acetylated alpha-linked acidic dipeptidase 2
Gene ID: 10003
Gene Synonyms: GCPIII; GPCIII; NAADALASE2; NAALADASE2
ORF Size: 2223 bp
RefSeq#: NM_005467
Gene Description: NAALAD2 is a member of the N-acetylated alpha-linked acidic dipeptidase (NAALADase) gene family. The representative member of this family is the gene encoding human prostate-specific membrane antigen (PSM), which is a marker of prostatic carcinomas and is the first to be shown to possess NAALADase activity. NAALADase cleaves N-acetyl-L-aspartate-L-glutamate (NAAG), which is a neuropeptide expressed both in the central nervous systems and in the periphery and is thought to function as a neurotransmitter. The product of this gene is a type II integral membrane protein. Transient transfection of this gene confers both NAALADase and dipetidyl peptidase IV activities to mammalian cells. NAALAD2 is highly expressed in ovary and testis as well as within discrete brain areas.
UniGene ID: Hs.503560
HGNC ID: HGNC:14526