human MYO6 shRNA silencing AAV

Name
AAV-h-MYO6-shRNA

Cat No
shAAV-216222

Availability
6-8 weeks

This is an AAV expressing shRNA for silencing of Human MYO6.

shAAV-216222

AAV-h-MYO6-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human MYO6 (myosin VI). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

DFNA22; DFNB37

Description (Vector)

MYO6 encodes a protein involved intracellular vesicle and organelle transport, especially in the hair cell of the inner ear. Mutations in this gene have been found in patients with non-syndromic autosomal dominant and recessive hearing loss.

Gene ID

4646

Gene Name (Vector)

myosin VI

Gene Symbol

MYO6

HGNC ID

HGNC:7605

ORF Size (aa)

3858

ORF Size (bp)

3858 bp

RefSeq ID

NM_004999

RefSeq Synonyms

NM_004999, NM_001300899, BC146764,

Species

human

UniGene ID

Hs.149387

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.