human MYL3 shRNA silencing AAV

Name
AAV-h-MYL3-shRNA

Cat No
shAAV-216184

Availability
6-8 weeks

This is an AAV expressing shRNA for silencing of Human MYL3.

shAAV-216184

AAV-h-MYL3-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human MYL3 (myosin light chain 3). Available with optional GFP reporter or cell-specific promoter.

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Vector Designer

Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

CMH8; MLC-lV/sb; MLC1SB; MLC1V; VLC1; VLCl

Description (Vector)

MYL3 encodes myosin light chain 3, an alkali light chain also referred to in the literature as both the ventricular isoform and the slow skeletal muscle isoform. Mutations in MYL3 have been identified as a cause of mid-left ventricular chamber type hypertrophic cardiomyopathy.

Gene ID

4634

Gene Name (Vector)

myosin light chain 3

Gene Symbol

MYL3

HGNC ID

HGNC:7584

ORF Size (aa)

588

RefSeq ID

NM_000258

RefSeq Synonyms

NM_000258, BC009790,

Species

human

UniGene ID

Hs.517939

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.