human MYD88 shRNA silencing AAV

Name
AAV-h-MYD88-shRNA

Cat No
shAAV-216145

Availability
6-8 weeks

This is an AAV expressing shRNA for silencing of Human MYD88.

shAAV-216145

AAV-h-MYD88-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human MYD88 (myeloid differentiation primary response 88). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

MYD88D

Description (Vector)

MYD88 encodes a cytosolic adapter protein that plays a central role in the innate and adaptive immune response. This protein functions as an essential signal transducer in the interleukin-1 and Toll-like receptor signaling pathways. These pathways regulate that activation of numerous proinflammatory genes. The encoded protein consists of an N-terminal death domain and a C-terminal Toll-interleukin1 receptor domain. Patients with defects in this gene have an increased susceptibility to pyogenic bacterial infections. Alternate splicing results in multiple transcript variants.

Gene ID

4615

Gene Name (Vector)

myeloid differentiation primary response 88

Gene Symbol

MYD88

HGNC ID

HGNC:7562

ORF Size (aa)

891

ORF Size (bp)

891 bp

RefSeq ID

NM_002468

RefSeq Synonyms

NM_002468, NM_001172569, NM_001172568, NM_001172567, NM_001172566, BC013589,

Species

human

UniGene ID

Hs.82116

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.